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Bylvay® (odevixibat)

Bylvay® (odevixibat)

Bylvay is a non-systemic ileal bile acid transport inhibitor (IBATi), it acts locally in the distal ileum to decrease the re-uptake of bile acids (primarily the salt forms) and increase the clearance of bile acids through the colon, reducing the concentration of bile acids in the serum. Bylvay treats:

  • Progressive familial intrahepatic cholestasis (PFIC) in patients aged 6 months or older
  • Cholestatic pruritus in Alagille syndrome (ALGS) in patients aged 6 months or older

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