{"id":85033,"date":"2025-12-03T06:00:15","date_gmt":"2025-12-03T04:00:15","guid":{"rendered":"https:\/\/www.ipsen.com\/sgp\/?page_id=85033"},"modified":"2025-12-03T07:51:26","modified_gmt":"2025-12-03T05:51:26","slug":"iqirvo-elafibranor","status":"publish","type":"page","link":"https:\/\/www.ipsen.com\/singapore\/products\/iqirvo-elafibranor\/","title":{"rendered":"Iqirvo\u00ae (elafibranor)"},"content":{"rendered":"    <section class=\"sub-page-banner bg-color-enabled  banner-no-filter\" style=\"background: linear-gradient(93.64deg, #224A81 2.99%, #2797D3 97.01%)\">\n                <div class=\"container content-sec\">\n            <nav aria-label=\"breadcrumb banner-font-color-blue\">\n            <ol class=\"breadcrumb\">\n                <li class=\"breadcrumb-item\"><a href=\"https:\/\/www.ipsen.com\/singapore\">Home<\/a><\/li><li class=\"breadcrumb-item visible\"><a href=\"https:\/\/www.ipsen.com\/singapore\/products\/\">Products<\/a><\/li><li class=\"breadcrumb-item active\"><a class=\"link-pointer-events-none\" href=\"#\" aria-current=\"page\">Iqirvo\u00ae (elafibranor)<\/a><\/li><\/ol>\n            <\/nav>            <h1 class=\"visible banner-font-color-white\">Iqirvo\u00ae (elafibranor)<\/h1>\n            <p class=\"hidden banner-font-color-white\"><\/p>\n        <\/div>\n    <\/section>\n\n\n\n\n<!--Alert Card Layout Start Here-->\n<section class=\"alertcard-section\">\n      <div class=\"container\">\n        <!--Alert Box HTML Start Here-->\n        <div class=\"alert-box warning-box\">\n                    <div class=\"info-icon\">\n              <span class=\"info-circle\"><img decoding=\"async\" src=\"https:\/\/www.ipsen.com\/singapore\/wp-content\/themes\/ipsen-main\/dist\/images\/alert-warning-icon.png\" alt=\"Alert\"\/><\/i>\n            <\/div>\n                    <div class=\"info-contents\">\n          <h4 role=\"heading\" aria-level=\"2\" class=\"info-head heading-four heading-four\"><\/h4>\n            <p class=\"info-sub-head-para hidden heading-para\"><\/p>\n            <div class=\"alert-content visible\"><p>Product availability, name and indicated use may vary by country. Please contact your local Ipsen website to learn more about products available in your country.<\/p>\n<\/div>\n          <\/div>\n        <\/div>\n        <!--Alert Box HTML Start Here-->\n      <\/div>\n    <\/section>\n<!--Alert Card Layout End Here-->\n\n\n<!-- Text & Media Block Code -->\n<section class=\"two-col-section text-media-section\">\n    <div class=\"container two-section-innner \">\n        <div class=\"response-inner\" style=\"background-image: url('')\">\n            <div class=\"row \">\n                <div class=\"col-xs-12 col-sm-12 col-md-6\">\n                                                    <div class=\"img-video-section\">\n                                <img decoding=\"async\" \n                                    src=\"https:\/\/www.ipsen.com\/singapore\/wp-content\/uploads\/sites\/28\/2025\/12\/Iqirvo_700x420_white.png\" \n                                    alt=\"\" \n                                >\n                            <\/div>\n                                        <\/div>\n                <div class=\" col-xs-12 col-sm-12 col-md-6\">\n                    <div class=\"section-content\">\n                        <div class=\"heading-dash\">\n                                                            <span class=\"dash\"><\/span>\n                                <h4 class=\"heading-para heading-four\" role=\"heading\" aria-level=\"2\">\n                                    Iqirvo\u00ae (elafibranor)                                <\/h4>\n                                                    <\/div>\n                                                <p>Iqirvo is an oral, once-daily, peroxisome proliferator-activated receptor alpha\/delta (PPAR \u03b1\/\u03b4) agonist approved for primary biliary cholangitis (PBC). Activation of PPAR\u03b1 inhibits molecules that promote inflammation, it decreases bile toxicity and mitigates oxidative stress. PPAR\u03b4 enhances bile flow, energy metabolism and anti-fibrotic pathways. The dual activation of PPAR-\u03b1 and PPAR-\u03b4 works synergistically to address cholestasis, inflammation, and fibrosis in PBC. Iqirvo has been granted accelerated approval in the US and conditional approval in EU for the treatment of primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults who have an inadequate response to UDCA, or as monotherapy in patients unable to tolerate UDCA.<\/p>\n                            <a \n                            aria-label=\" about Iqirvo\u00ae (elafibranor)\"  \n                                role=\"link\" \n                                class=\"btn-link hidden\"\n                                href=\"\" \n                                target=\"_self\"\n                            > \n                                 \n                            <\/a>\n\n                    <\/div>\n                <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/section>\n\n    <section id=\"carouselDocumentControls\" class=\"document-card mt-5\" >\n        <div class=\"container\">\n            <div 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src=\"https:\/\/www.ipsen.com\/singapore\/wp-content\/themes\/ipsen-main\/dist\/images\/doc-icon1.png\" alt=\"\" width=\"100%\">\n                                            <\/a>\n                                        <\/div>\n                                    <\/div>\n                                    <div class=\"column-2 col-lg-10 col-md-10 col-sm-12\">\n                                        <div class=\"doc-card-contents\">\n                                            <div class=\"top-info-bar\">\n                                                <div class=\"left-contents\">\n                                                    <div class=\"report-detail\">\n                                                        <button role=\"presentation\" tabindex=\"-1\" class=\"btn report-btn hidden\" >\n                                                                                                                    <\/button>\n                                                    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href=\"https:\/\/www.ipsen.com\/singapore\/wp-content\/uploads\/sites\/28\/2025\/10\/Iqirvo-Package-Insert.pdf\" target=\"_blank\">Iqirvo Package Insert<\/a><\/h5>\n                                                                                                            <span class=\"pdf\">\n                                                            <img decoding=\"async\" src=\"https:\/\/www.ipsen.com\/singapore\/wp-content\/themes\/ipsen-main\/dist\/images\/pdf.png\" alt=\"Download\" title=\"Download\">\n                                                            <span class=\"pdf-text\">\n                                                                (361 KB)\n                                                            <\/span>\n                                                        <\/span>\n                                                                                                    <\/div>\n                                                <p><\/p>\n                      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