{"id":34102,"date":"2023-06-28T08:49:51","date_gmt":"2023-06-28T06:49:51","guid":{"rendered":"https:\/\/www.ipsen.com\/?p=34102"},"modified":"2023-06-28T08:49:53","modified_gmt":"2023-06-28T06:49:53","slug":"faire-progresser-la-prise-en-charge-de-la-cholangite-biliaire-primitive-cbp-les-eclairages-dexperts","status":"publish","type":"post","link":"https:\/\/www.ipsen.com\/fr\/actualites\/rare-diseases-fr\/faire-progresser-la-prise-en-charge-de-la-cholangite-biliaire-primitive-cbp-les-eclairages-dexperts\/","title":{"rendered":"Faire progresser la prise en charge de la cholangite biliaire primitive (CBP) : les \u00e9clairages d&rsquo;experts\u00a0"},"content":{"rendered":"    <section class=\"video-card \">\n        <div class=\"container\">\n            <!-- Block Details -->\n            <div class=\"video-card-header\">\n                <h3 class=\"video-card-block-title hidden heading-three\">\n                                    <\/h3>\n                <p class=\"charcoal-grey video-card-block-summary hidden\"> \n                                    <\/p>\n            <\/div>\n\n            <!-- Video Iframe embed -->\n                            <div class=\"video-embed\"> \n                <iframe loading=\"lazy\" title=\"Comms_PBC_Thought Leadership PBCSG Members_Marco Full Video2\" src=\"https:\/\/player.vimeo.com\/video\/840342825?app_id=122963&#038;autoplay=1&#038;muted=1&#038;controls=1&#038;loop=1&#038;autopause=1&#038;background=0\" width=\"640\" height=\"360\" frameborder=\"0\" allow=\"autoplay; fullscreen; picture-in-picture; clipboard-write; encrypted-media; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" frameborder=\"0\" allow=\"autoplay; fullscreen; picture-in-picture\" data-ot-ignore><\/iframe>                <\/div>\n            \n            <!-- Block CTA -->\n            <div class=\"cta-block hidden\">\n                            <\/div>\n\n        <\/div>\n    <\/section>\n\n\n    <section class=\"video-card \">\n        <div class=\"container\">\n            <!-- Block Details -->\n            <div class=\"video-card-header\">\n                <h3 class=\"video-card-block-title hidden heading-three\">\n                                    <\/h3>\n                <p class=\"charcoal-grey video-card-block-summary hidden\"> \n                                    <\/p>\n            <\/div>\n\n            <!-- Video Iframe embed -->\n                            <div class=\"video-embed\"> \n                <iframe loading=\"lazy\" title=\"Comms PBC Thought Leadership PBCSG Members Gideon Full Video\" src=\"https:\/\/player.vimeo.com\/video\/840095865?app_id=122963&#038;autoplay=1&#038;muted=1&#038;controls=1&#038;loop=1&#038;autopause=1&#038;background=0\" width=\"640\" height=\"360\" frameborder=\"0\" allow=\"autoplay; fullscreen; picture-in-picture; clipboard-write; encrypted-media; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" frameborder=\"0\" allow=\"autoplay; fullscreen; picture-in-picture\" data-ot-ignore><\/iframe>                <\/div>\n            \n            <!-- Block CTA -->\n            <div class=\"cta-block hidden\">\n                            <\/div>\n\n        <\/div>\n    <\/section>\n\n\n\n<p><strong><em>\u00ab\u202fNous sommes \u00e0 l&rsquo;aube d&rsquo;un cataclysme dans notre approche de la prise en charge de la CBP.\u202f\u00bb<\/em><\/strong> \u2013 Professeur Gideon Hirschfield, H\u00e9patologue et Professeur de m\u00e9decine \u00e0 l&rsquo;Universit\u00e9 de Toronto.&nbsp;<\/p>\n\n\n\n<p>La cholangite biliaire primitive (CBP) est une maladie h\u00e9patique auto-immune rare, provoquant une inflammation chronique des voies biliaires. Elle peut avoir un impact consid\u00e9rable sur la qualit\u00e9 de vie d&rsquo;une personne. Si elle n&rsquo;est pas trait\u00e9e, la CBP peut entra\u00eener une mort pr\u00e9matur\u00e9e <sup>1<\/sup>.&nbsp;<\/p>\n\n\n\n<p>\u202f&nbsp;<\/p>\n\n\n\n<p><strong><em>\u00ab\u202fIl est important de regarder au-del\u00e0 du foie pour am\u00e9liorer la qualit\u00e9 de vie des patients, nous devrions suivre une approche holistique de la CBP.\u202f\u00bb<\/em><\/strong> \u2013 Dr Marco Carbone, H\u00e9patologue et charg\u00e9 d&rsquo;enseignement clinique \u00e0 l&rsquo;Universit\u00e9 de Milan.&nbsp;<\/p>\n\n\n\n<p>Les th\u00e9rapies actuellement propos\u00e9es dans la CBP ne traitent pas les sympt\u00f4mes potentiellement invalidants de la maladie, tels que le prurit chronique (d\u00e9mangeaisons) et la fatigue<sup>2<\/sup>. Dans certains cas, un prurit s\u00e9v\u00e8re peut entra\u00eener une privation de sommeil, une d\u00e9pression et des id\u00e9es suicidaires<sup>3<\/sup>.&nbsp;<\/p>\n\n\n\n<p><strong><em>\u00ab\u202fC&rsquo;est un but commun aux m\u00e9decins et patients, non seulement que nos patients vivent plus longtemps, mais \u00e9galement qu&rsquo;ils se sentent mieux et vivent mieux, aujourd&rsquo;hui et demain.\u202f\u00bb<\/em><\/strong> \u2013 Professeur Gideon Hirschfield, H\u00e9patologue et professeur de m\u00e9decine \u00e0 l&rsquo;Universit\u00e9 de Toronto.&nbsp;<\/p>\n\n\n\n<p>\u00c0 l&rsquo;occasion du 10<sup>\u00e8me<\/sup> anniversaire du Global PBC Study Group, d&rsquo;\u00e9minents experts dans le domaine des maladies h\u00e9patiques rares, plusieurs associations de patients ainsi que des repr\u00e9sentants de l&rsquo;industrie se sont r\u00e9unis \u00e0 Rotterdam pour discuter des derni\u00e8res recherches et d\u00e9couvertes sur la prise en charge de la CBP. Au terme de l&rsquo;\u00e9v\u00e9nement, nous avons eu l&rsquo;opportunit\u00e9 d&rsquo;\u00e9changer avec le Pr Gideon Hirschfield et le Dr Marco Carbone sur l&rsquo;importance d&rsquo;am\u00e9liorer la qualit\u00e9 de vie des patients parall\u00e8lement aux r\u00e9sultats cliniques dans la prise en charge de la CBP.&nbsp;<\/p>\n\n\n\n<p><strong><em>\u00ab Je crois que les patients s&rsquo;affirment de plus en plus. Ils s&rsquo;approprient davantage la maladie et sont plus impliqu\u00e9s dans leur prise en charge.\u202f\u00bb<\/em><\/strong><em> \u2013<\/em> Dr Marco Carbone, H\u00e9patologue et charg\u00e9 d&rsquo;enseignement clinique \u00e0 l&rsquo;Universit\u00e9 de Milan<strong><em>.<\/em><\/strong>&nbsp;<\/p>\n\n\n\n<p><strong>R\u00e9f\u00e9rences\u202f:<\/strong>&nbsp;<\/p>\n\n\n\n<p>1. Younossi ZM, <em>et al<\/em>. 2019. Diagnosis and Management of Primary Biliary Cholangitis. <em>Am J Gastroenterol<\/em>. 114(1):48\u201363.&nbsp;<\/p>\n\n\n\n<p>2. Aguilar MT and Chascsa, D.M., 2020. Update on emerging treatment options for primary biliary cholangitis.\u202f<em>Hepat Med<\/em>. p.69-77.&nbsp;<\/p>\n\n\n\n<p>3. Gungabissoon U, <em>et al.<\/em> 2022. Disease burden of primary biliary cholangitis and associated pruritus based on a cross-sectional US claims analysis.\u202f<em>BMJ Open Gastro<\/em>.\u202f9(1):.e000857.&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00ab\u202fNous sommes \u00e0 l&rsquo;aube d&rsquo;un cataclysme dans notre approche de la prise en charge de la CBP.\u202f\u00bb \u2013 Professeur Gideon<\/p>\n","protected":false},"author":11,"featured_media":34069,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1192],"tags":[],"class_list":["post-34102","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-rare-diseases-fr","entry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Faire progresser la prise en charge de la cholangite biliaire primitive (CBP) : les 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