{"id":104278,"date":"2026-11-12T08:30:07","date_gmt":"2026-11-12T06:30:07","guid":{"rendered":"https:\/\/www.ipsen.com\/cn\/?post_type=press_release&#038;p=104278"},"modified":"2026-11-12T08:30:10","modified_gmt":"2026-11-12T06:30:10","slug":"%e5%85%a8%e7%90%83%e8%b5%84%e8%ae%af%ef%bc%9a%e4%be%9d%e9%9d%9e%e5%85%b0%e8%af%ba%e5%8f%91%e5%b8%83%e6%9c%80%e6%96%b0%e7%aa%81%e7%a0%b4%e6%80%a7%e7%a0%94%e7%a9%b6%e6%95%b0%e6%8d%ae%ef%bc%8c%e6%8e%a8","status":"publish","type":"press_release","link":"https:\/\/www.ipsen.com\/cn\/press-releases\/%e5%85%a8%e7%90%83%e8%b5%84%e8%ae%af%ef%bc%9a%e4%be%9d%e9%9d%9e%e5%85%b0%e8%af%ba%e5%8f%91%e5%b8%83%e6%9c%80%e6%96%b0%e7%aa%81%e7%a0%b4%e6%80%a7%e7%a0%94%e7%a9%b6%e6%95%b0%e6%8d%ae%ef%bc%8c%e6%8e%a8\/","title":{"rendered":"\u5168\u7403\u8d44\u8baf\uff1a\u4f9d\u975e\u5170\u8bfa\u53d1\u5e03\u6700\u65b0\u7a81\u7834\u6027\u7814\u7a76\u6570\u636e\uff0c\u63a8\u52a8\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\u6cbb\u7597\u8fc8\u5411\u66f4\u9ad8\u76ee\u6807\uff0c\u7814\u7a76\u4e2d\u8d85\u8fc785%\u7684\u6cbb\u7597\u60a3\u8005\u5b9e\u73b0\u78b1\u6027\u78f7\u9178\u9176\u6b63\u5e38\u5316"},"content":{"rendered":"\n<ul class=\"wp-block-list\">\n<li>ELSPIRE\u7814\u7a76\u7ed3\u679c\u4f5c\u4e3a\u6700\u65b0\u7a81\u7834\u6027\u7814\u7a76\u6570\u636e\uff0c\u57282026\u5e74\u7f8e\u56fd\u809d\u75c5\u7814\u7a76\u5b66\u4f1a\u809d\u75c5\u5e74\u4f1a\uff08The Liver Meeting<sup>\u00ae<\/sup>\u00a02026\uff09\u4e0a\u516c\u5e03\uff0c\u5e76\u540c\u6b65\u53d1\u8868\u4e8e\u8be5\u5b66\u4f1a\u65d7\u8230\u671f\u520a\u300a\u809d\u810f\u75c5\u5b66\u300b\uff08HEPATOLOGY\uff09<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u7b2c52\u5468\u65f6\uff0c85.3% \u63a5\u53d7\u4f9d\u975e\u5170\u8bfa\u6cbb\u7597\u7684\u5165\u7ec4\u60a3\u8005\u5b9e\u73b0\u78b1\u6027\u78f7\u9178\u9176\uff08ALP\uff09\u6b63\u5e38\u5316\uff0c\u5b89\u6170\u5242\u7ec4\u4e3a23.3%\uff1b\u4f9d\u975e\u5170\u8bfa\u603b\u4f53\u8010\u53d7\u6027\u826f\u597d<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u7814\u7a76\u7ed3\u679c\u8fdb\u4e00\u6b65\u4e30\u5bcc\u4e86\u73b0\u6709\u8bc1\u636e\uff0c\u652f\u6301\u5c06ALP\u6b63\u5e38\u5316\u4f5c\u4e3a\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\uff08PBC\uff09\u60a3\u8005\u53ef\u5b9e\u73b0\u7684\u6cbb\u7597\u76ee\u6807<\/li>\n<\/ul>\n\n\n<p class=\"heading-para wp-block-paragraph\">\u3000\u3000\u76ca\u666e\u751f\u8fd1\u65e5\u516c\u5e03\u4e86ELSPIRE \u2162\u671f\u7814\u7a76\u7684\u6700\u65b0\u7a81\u7834\u6027\u7814\u7a76\u6570\u636e\uff0c\u8be5\u7814\u7a76\u7eb3\u5165\u4e86\u78b1\u6027\u78f7\u9178\u9176\uff08ALP\uff09\u6c34\u5e73\u4e3a\u6b63\u5e38\u503c\u4e0a\u9650\uff08ULN\uff091\u81f31.67\u500d\u7684\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\uff08PBC\uff09\u60a3\u8005\u3002ALP\u662f\u8861\u91cf\u75be\u75c5\u6d3b\u52a8\u5ea6\u7684\u4e00\u9879\u751f\u5316\u6307\u6807\u3002\u7b2c52\u5468\u65f6\uff0c85.3%\u63a5\u53d7\u4f9d\u975e\u5170\u8bfa\u6cbb\u7597\u7684\u60a3\u8005ALP\u8fbe\u5230\u6b63\u5e38\u6c34\u5e73\uff0c\u5b89\u6170\u5242\u7ec4\u4e3a23.3%\uff08p&lt;0.0001\uff09\u3002\u7814\u7a76\u7ed3\u679c\u4f5c\u4e3a\u6700\u65b0\u7a81\u7834\u6027\u7814\u7a76\u6570\u636e\uff0c\u57282026\u5e74\u7f8e\u56fd\u809d\u75c5\u7814\u7a76\u5b66\u4f1a\uff08AASLD\uff09\u809d\u75c5\u5e74\u4f1a\uff08The Liver Meeting\u00ae 2026\uff09\u4e0a\u516c\u5e03\uff0c\u5e76\u540c\u6b65\u53d1\u8868\u4e8e\u300a\u809d\u810f\u75c5\u5b66\u300b\uff08HEPATOLOGY\uff09<sup>1<\/sup>\u3002\u6b64\u5916\uff0c\u8fd9\u4e9b\u6db5\u76d6\u66f4\u5e7f\u6cdb\u60a3\u8005\u4eba\u7fa4\u7684\u6570\u636e\u6b63\u5728\u5411\u76d1\u7ba1\u673a\u6784\u9012\u4ea4\u3002<\/p>\n\n<p class=\"heading-para wp-block-paragraph\">\u3000\u3000\u7f8e\u56fd\u77e5\u540d\u809d\u75c5\u7814\u7a76\u4e2d\u5fc3Liver Institute Northwest\u3001Velocity \u4e34\u5e8a\u7814\u7a76\u673a\u6784\u53ca\u534e\u76db\u987f\u5dde\u7acb\u5927\u5b66\u533b\u5b66\u535a\u58ebKris V. 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wp-block-paragraph\">\u3000\u3000\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\uff08PBC\uff09\u662f\u4e00\u79cd\u7f55\u89c1\u3001\u8fdb\u884c\u6027\u81ea\u8eab\u514d\u75ab\u6027\u809d\u810f\u75be\u75c5\uff0c\u53ef\u5bfc\u81f4\u809d\u7ea4\u7ef4\u5316\u3001\u809d\u786c\u5316\u53ca\u809d\u529f\u80fd\u8870\u7aed\u3002\u957f\u671f\u4ee5\u6765\uff0cALP\u2265\u00a01.67\u00a0ULN\u6b63\u5e38\u503c\u4e0a\u9650\u901a\u5e38\u88ab\u5b9a\u4e49\u4e3a\u6cbb\u7597\u5e94\u7b54\u4e0d\u8db3\uff0c\u56e0\u6b64\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8c\u4e3b\u8981\u96c6\u4e2d\u5728\u8fbe\u5230\u6216\u8d85\u8fc7\u8fd9\u4e00\u9608\u503c\u7684\u60a3\u8005\u7fa4\u4f53\u3002\u7136\u800c\uff0c\u7814\u7a76\u663e\u793a\uff0cALP\u9ad8\u4e8e\u6b63\u5e38\u503c\u4e0a\u9650\uff0c\u5373\u63d0\u793a\u75be\u75c5\u4ecd\u5904\u4e8e\u6d3b\u52a8\u72b6\u6001\uff0c\u5e76\u4e0e\u60a3\u8005\u65e0\u809d\u79fb\u690d\u751f\u5b58\u671f\u51cf\u5c11\u76f8\u5173\uff1b\u76f8\u53cd\uff0cALP\u6b63\u5e38\u5316\u5219\u4e0e\u66f4\u9ad8\u7684\u65e0\u5e76\u53d1\u75c7\u751f\u5b58\u7387\u76f8\u5173<sup>2 3<\/sup>\u3002\u56e0\u6b64\uff0cELSPIRE\u7814\u7a76\u4e13\u95e8\u8bc4\u4f30\u4e86ALP\u5904\u4e8e\u6b63\u5e38\u503c\u4e0a\u96501\u81f31.67\u500d\u4e4b\u95f4\u60a3\u8005\u63a5\u53d7\u4f9d\u975e\u5170\u8bfa\u6cbb\u7597\u7684\u6548\u679c\u3002\u8fd9\u4e00\u60a3\u8005\u7fa4\u4f53\u6b64\u524d\u5c1a\u672a\u5728\u4f9d\u975e\u5170\u8bfa\u6ce8\u518c\u6027\u4e34\u5e8a\u7814\u7a76\u4e2d\u8fdb\u884c\u7cfb\u7edf\u8bc4\u4f30\u3002<\/p>\n\n<p class=\"heading-para wp-block-paragraph\">\u3000\u3000PBC\u60a3\u8005\u7ec4\u7ec7PBCers\u4e3b\u5e2dCarol Roberts\u8868\u793a\uff1a\u201c\u968f\u7740\u8fd1\u5e74\u6765PBC\u75be\u75c5\u7ba1\u7406\u4e0d\u65ad\u8fdb\u5c55\uff0c\u4ee4\u4eba\u9f13\u821e\u7684\u662f\uff0c\u6211\u4eec\u53ef\u4ee5\u4e3aPBC\u6cbb\u7597\u8bbe\u5b9a\u66f4\u9ad8\u76ee\u6807\u3002\u6709\u6548\u6cbb\u7597\u4e0d\u4ec5\u610f\u5473\u7740\u964d\u4f4e\u5173\u952e\u809d\u529f\u80fd\u6307\u6807\uff0c\u66f4\u610f\u5473\u7740\u80fd\u591f\u5c06ALP\u7b49\u53cd\u6620\u75be\u75c5\u6d3b\u52a8\u7a0b\u5ea6\u7684\u91cd\u8981\u6307\u6807\u6062\u590d\u81f3\u6b63\u5e38\u8303\u56f4\u3002\u201d<\/p>\n\n<p class=\"heading-para wp-block-paragraph\">\u3000\u3000PBC\u5021\u5bfc\u7ec4\u7ec7PBC Awareness\u521b\u59cb\u4eba\u517c\u4e3b\u5e2dL. Marie Asad\u8868\u793a\uff1a\u201c\u5bf9\u4e8ePBC\u60a3\u8005\u800c\u8a00\uff0c\u4fdd\u62a4\u809d\u810f\u4e0e\u6539\u5584\u5f71\u54cd\u65e5\u5e38\u751f\u6d3b\u7684\u75c7\u72b6\u540c\u6837\u91cd\u8981\u3002\u6211\u4eec\u5e0c\u671b\uff0c\u5728\u8c08\u53ca\u75b2\u52b3\u548c\u7619\u75d2\u65f6\uff0c\u533b\u7597\u56e2\u961f\u80fd\u591f\u503e\u542c\u6211\u4eec\u7684\u58f0\u97f3\uff0c\u5e76\u5c06\u8fd9\u4e9b\u95ee\u9898\u7eb3\u5165\u6cbb\u7597\u8003\u91cf\u3002\u771f\u6b63\u6709\u610f\u4e49\u7684\u8fdb\u6b65\uff0c\u662f\u5728\u7ba1\u7406\u75be\u75c5\u7684\u540c\u65f6\uff0c\u5e2e\u52a9\u6211\u4eec\u6d3b\u5f97\u66f4\u597d\u3002\u201d<\/p>\n\n<p class=\"heading-para wp-block-paragraph\">\u3000\u3000\u76ca\u666e\u751f\u8fd8\u5c06\u516c\u5e03\u5176\u4e0d\u65ad\u6269\u5c55\u7684\u7f55\u89c1\u80c6\u6c41\u6de4\u79ef\u6027\u809d\u75c5\u4ea7\u54c1\u7ec4\u5408\u7684\u6700\u65b0\u7814\u7a76\u6570\u636e\uff0c\u5305\u62ec\u7528\u4e8e\u6cbb\u7597\u8fdb\u884c\u6027\u5bb6\u65cf\u6027\u809d\u5185\u80c6\u6c41\u6de4\u79ef\u75c7\u548c\u963f\u62c9\u6770\u91cc\u7efc\u5408\u5f81\u7684\u6700\u65b0\u6210\u679c\u3002\u76ee\u524d\uff0c\u76ca\u666e\u751f\u5df2\u6709\u4e24\u6b3e\u836f\u7269\u5728\u4e0d\u540c\u56fd\u5bb6\u548c\u5730\u533a\u83b7\u6279\u7528\u4e8e\u4e09\u79cd\u4e0d\u540c\u7684\u7f55\u89c1\u80c6\u6c41\u6de4\u79ef\u6027\u809d\u75c5\u3002\u9488\u5bf9\u6cbb\u7597\u9700\u6c42\u4e9f\u5f85\u6ee1\u8db3\u548c\u6cbb\u7597\u9009\u62e9\u6709\u9650\u7684\u75be\u75c5\u9886\u57df\uff0c\u76ca\u666e\u751f\u6301\u7eed\u63a8\u8fdb\u521b\u65b0\u7814\u53d1\uff0c\u63a8\u52a8\u6cbb\u7597\u8fdb\u6b65\u3002\u901a\u8fc7\u805a\u7126\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\u3001\u539f\u53d1\u6027\u786c\u5316\u6027\u80c6\u7ba1\u708e\u3001\u8fdb\u884c\u6027\u5bb6\u65cf\u6027\u809d\u5185\u80c6\u6c41\u6de4\u79ef\u75c7\u53ca\u963f\u62c9\u6770\u91cc\u7efc\u5408\u5f81\u7b49\u75be\u75c5\uff0c\u76ca\u666e\u751f\u81f4\u529b\u4e8e\u6539\u5584\u60a3\u8005\u7684\u6cbb\u7597\u7ed3\u5c40\u4e0e\u751f\u6d3b\u8d28\u91cf\u3002<strong><\/strong><\/p>\n\n<p class=\"heading-para wp-block-paragraph\"><strong style=\"font-weight: bold\">\u58f0\u660e<\/strong><strong><\/strong><\/p>\n\n\n<ul class=\"wp-block-list\">\n<li>\u672c\u8d44\u6599\u65e8\u5728\u4f20\u9012\u533b\u5b66\u524d\u6cbf\u4fe1\u606f\u548c\u7814\u7a76\u8fdb\u5c55\uff0c\u975e\u63a8\u5e7f\u7528\u9014<\/li>\n\n\n\n<li>\u622a\u81f3\u672c\u7a3f\u4ef6\u53d1\u5e03\u4e4b\u65e5\uff0c\u4f9d\u975e\u5170\u8bfa\u5c1a\u672a\u5728\u4e2d\u56fd\u83b7\u6279<\/li>\n\n\n\n<li>\u622a\u81f3\u672c\u7a3f\u4ef6\u53d1\u5e03\u4e4b\u65e5\uff0c\u963f\u62c9\u6770\u91cc\u7efc\u5408\u5f81\u9002\u5e94\u75c7\u5c1a\u672a\u5728\u4e2d\u56fd\u83b7\u6279<\/li>\n\n\n\n<li>\u672c\u6587\u4e0d\u6784\u6210\u533b\u7597\u5efa\u8bae\u3002\u6709\u5173\u75be\u75c5\u8bca\u7597\u95ee\u9898\uff0c\u8bf7\u54a8\u8be2\u533b\u7597\u536b\u751f\u4e13\u4e1a\u4eba\u58eb<\/li>\n<\/ul>\n\n\n<p class=\"heading-para wp-block-paragraph\"><strong style=\"font-weight: bold\">\u5ba1\u6279\u7801<\/strong><strong><\/strong><\/p>\n\n<p class=\"heading-para wp-block-paragraph\">IQV-CN-000003<\/p>\n\n<p class=\"heading-para wp-block-paragraph\"><strong style=\"font-weight: bold\">\u539f\u6587\u94fe\u63a5<\/strong><strong><\/strong><\/p>\n\n<p class=\"heading-para wp-block-paragraph\"><a href=\"https:\/\/www.ipsen.com\/press-release\/iqirvo-late-breaking-data-raises-ambitions-in-pbc-with-more-than-85-of-patients-on-treatment-achieving-alp-normalization-3396826\">https:\/\/www.ipsen.com\/press-release\/iqirvo-late-breaking-data-raises-ambitions-in-pbc-with-more-than-85-of-patients-on-treatment-achieving-alp-normalization-3396826<\/a><\/p>\n\n<p class=\"heading-para wp-block-paragraph\"><strong style=\"font-weight: bold\">\u53c2\u8003\u6587\u732e<\/strong><strong><\/strong><\/p>\n\n\n<p style=\"font-size:14px\">1. Kowdley. K,et al. Treatment with elafibranor to normalize alkaline phosphatase in patients with primary biliary cholangitis and incomplete response to ursodeoxycholic acid: Results from the phase III randomized controlled ELSPIRE trial. <em>Hepatol.<\/em>&nbsp;2026 Nov <a href=\"https:\/\/eur01.safelinks.protection.outlook.com\/?url=https%3A%2F%2Fwww.doi.org%2F10.1097%2FHEP.0000000000001906&amp;data=05%7C02%7Csally.bain%40ipsen.com%7C579da776e7364329c6ca08df38f21188%7C9e776b6aa6cc4fafa054a502153beb01%7C0%7C0%7C639292284490391582%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=jBrhUlv%2BN3vGqLDSK0aEwuJrIv%2F4kQcqDmmcVpId2fs%3D&amp;reserved=0\"><u>https:\/\/www.doi.org\/10.1097\/HEP.0000000000001906<\/u><\/a>\n<br>\n2. Kowdley,,et al. Longitudinal Relationship Between Elevated Liver Biochemical Tests and Negative Clinical Outcomes in Primary Biliary Cholangitis: A Population-Based Study. Alimentary Pharmacology &amp; Therapeutics 2025;61:1775\u20131784. <br>\n3. Lammers, et al. Levels of Alkaline Phosphatase and Bilirubin Are Surrogate End Points of Outcomes of Patients With Primary Biliary Cirrhosis: An International Follow-up Study. Gastroenterology 2014;147:1338\u20131349.<br>\n4. Lleo, et al. Primary biliary cholangitis. The Lancet 2020:396: 1915 \u2013 1926<br>\n5. Tan et al. Global Epidemiology of Primary Biliary Cholangitis: An Updated Systematice Review and Meta-Analysis. Clin Gastroenterol Hepatol. 2026 Mar:24(3): 621-623 doi: 10.1016\/j.cgh.2025.03.025.<br>\n6. Trivella et al. Primary biliary cholangitis: Epidemiology, prognosis, and treatment. Hepatol Commun. 2023 Jun 2;7(6):e0179. doi:&nbsp;10.1097\/HC9.0000000000000179\n<\/p>\n\n\n<p class=\"heading-para wp-block-paragraph\"><\/p>","protected":false},"excerpt":{"rendered":"<p>\u3000\u3000\u76ca\u666e\u751f\u8fd1\u65e5\u516c\u5e03\u4e86ELSPIRE \u2162\u671f\u7814\u7a76\u7684\u6700\u65b0\u7a81\u7834\u6027\u7814\u7a76\u6570\u636e\uff0c\u8be5\u7814\u7a76\u7eb3\u5165\u4e86\u78b1\u6027\u78f7\u9178\u9176\uff08ALP\uff09\u6c34\u5e73\u4e3a\u6b63\u5e38\u503c\u4e0a\u9650\uff08ULN\uff091\u81f31.67\u500d\u7684\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\uff08PBC\uff09\u60a3\u8005\u3002ALP\u662f\u8861\u91cf\u75be\u75c5\u6d3b\u52a8\u5ea6\u7684\u4e00\u9879\u751f\u5316\u6307\u6807\u3002\u7b2c52\u5468\u65f6\uff0c85.3%\u63a5\u53d7\u4f9d\u975e\u5170\u8bfa\u6cbb\u7597\u7684\u60a3\u8005ALP\u8fbe\u5230\u6b63\u5e38\u6c34\u5e73\uff0c\u5b89\u6170\u5242\u7ec4\u4e3a23.3%\uff08p&lt;0.0001\uff09\u3002\u7814\u7a76\u7ed3\u679c\u4f5c\u4e3a\u6700\u65b0\u7a81\u7834\u6027\u7814\u7a76\u6570\u636e\uff0c\u57282026\u5e74\u7f8e\u56fd\u809d\u75c5\u7814\u7a76\u5b66\u4f1a\uff08AASLD\uff09\u809d\u75c5\u5e74\u4f1a\uff08The Liver Meeting\u00ae 2026\uff09\u4e0a\u516c\u5e03\uff0c\u5e76\u540c\u6b65\u53d1\u8868\u4e8e\u300a\u809d\u810f\u75c5\u5b66\u300b\uff08HEPATOLOGY\uff091\u3002\u6b64\u5916\uff0c\u8fd9\u4e9b\u6db5\u76d6\u66f4\u5e7f\u6cdb\u60a3\u8005\u4eba\u7fa4\u7684\u6570\u636e\u6b63\u5728\u5411\u76d1\u7ba1\u673a\u6784\u9012\u4ea4\u3002 \u3000\u3000\u7f8e\u56fd\u77e5\u540d\u809d\u75c5\u7814\u7a76\u4e2d\u5fc3Liver Institute Northwest\u3001Velocity \u4e34\u5e8a\u7814\u7a76\u673a\u6784\u53ca\u534e\u76db\u987f\u5dde\u7acb\u5927\u5b66\u533b\u5b66\u535a\u58ebKris V. 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Roberts\u8868\u793a\uff1a\u201c\u968f\u7740\u8fd1\u5e74\u6765PBC\u75be\u75c5\u7ba1\u7406\u4e0d\u65ad\u8fdb\u5c55\uff0c\u4ee4\u4eba\u9f13\u821e\u7684\u662f\uff0c\u6211\u4eec\u53ef\u4ee5\u4e3aPBC\u6cbb\u7597\u8bbe\u5b9a\u66f4\u9ad8\u76ee\u6807\u3002\u6709\u6548\u6cbb\u7597\u4e0d\u4ec5\u610f\u5473\u7740\u964d\u4f4e\u5173\u952e\u809d\u529f\u80fd\u6307\u6807\uff0c\u66f4\u610f\u5473\u7740\u80fd\u591f\u5c06ALP\u7b49\u53cd\u6620\u75be\u75c5\u6d3b\u52a8\u7a0b\u5ea6\u7684\u91cd\u8981\u6307\u6807\u6062\u590d\u81f3\u6b63\u5e38\u8303\u56f4\u3002\u201d \u3000\u3000PBC\u5021\u5bfc\u7ec4\u7ec7PBC Awareness\u521b\u59cb\u4eba\u517c\u4e3b\u5e2dL. Marie Asad\u8868\u793a\uff1a\u201c\u5bf9\u4e8ePBC\u60a3\u8005\u800c\u8a00\uff0c\u4fdd\u62a4\u809d\u810f\u4e0e\u6539\u5584\u5f71\u54cd\u65e5\u5e38\u751f\u6d3b\u7684\u75c7\u72b6\u540c\u6837\u91cd\u8981\u3002\u6211\u4eec\u5e0c\u671b\uff0c\u5728\u8c08\u53ca\u75b2\u52b3\u548c\u7619\u75d2\u65f6\uff0c\u533b\u7597\u56e2\u961f\u80fd\u591f\u503e\u542c\u6211\u4eec\u7684\u58f0\u97f3\uff0c\u5e76\u5c06\u8fd9\u4e9b\u95ee\u9898\u7eb3\u5165\u6cbb\u7597\u8003\u91cf\u3002\u771f\u6b63\u6709\u610f\u4e49\u7684\u8fdb\u6b65\uff0c\u662f\u5728\u7ba1\u7406\u75be\u75c5\u7684\u540c\u65f6\uff0c\u5e2e\u52a9\u6211\u4eec\u6d3b\u5f97\u66f4\u597d\u3002\u201d \u3000\u3000\u76ca\u666e\u751f\u8fd8\u5c06\u516c\u5e03\u5176\u4e0d\u65ad\u6269\u5c55\u7684\u7f55\u89c1\u80c6\u6c41\u6de4\u79ef\u6027\u809d\u75c5\u4ea7\u54c1\u7ec4\u5408\u7684\u6700\u65b0\u7814\u7a76\u6570\u636e\uff0c\u5305\u62ec\u7528\u4e8e\u6cbb\u7597\u8fdb\u884c\u6027\u5bb6\u65cf\u6027\u809d\u5185\u80c6\u6c41\u6de4\u79ef\u75c7\u548c\u963f\u62c9\u6770\u91cc\u7efc\u5408\u5f81\u7684\u6700\u65b0\u6210\u679c\u3002\u76ee\u524d\uff0c\u76ca\u666e\u751f\u5df2\u6709\u4e24\u6b3e\u836f\u7269\u5728\u4e0d\u540c\u56fd\u5bb6\u548c\u5730\u533a\u83b7\u6279\u7528\u4e8e\u4e09\u79cd\u4e0d\u540c\u7684\u7f55\u89c1\u80c6\u6c41\u6de4\u79ef\u6027\u809d\u75c5\u3002\u9488\u5bf9\u6cbb\u7597\u9700\u6c42\u4e9f\u5f85\u6ee1\u8db3\u548c\u6cbb\u7597\u9009\u62e9\u6709\u9650\u7684\u75be\u75c5\u9886\u57df\uff0c\u76ca\u666e\u751f\u6301\u7eed\u63a8\u8fdb\u521b\u65b0\u7814\u53d1\uff0c\u63a8\u52a8\u6cbb\u7597\u8fdb\u6b65\u3002\u901a\u8fc7\u805a\u7126\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\u3001\u539f\u53d1\u6027\u786c\u5316\u6027\u80c6\u7ba1\u708e\u3001\u8fdb\u884c\u6027\u5bb6\u65cf\u6027\u809d\u5185\u80c6\u6c41\u6de4\u79ef\u75c7\u53ca\u963f\u62c9\u6770\u91cc\u7efc\u5408\u5f81\u7b49\u75be\u75c5\uff0c\u76ca\u666e\u751f\u81f4\u529b\u4e8e\u6539\u5584\u60a3\u8005\u7684\u6cbb\u7597\u7ed3\u5c40\u4e0e\u751f\u6d3b\u8d28\u91cf\u3002 \u58f0\u660e \u5ba1\u6279\u7801 IQV-CN-000003 \u539f\u6587\u94fe\u63a5 https:\/\/www.ipsen.com\/press-release\/iqirvo-late-breaking-data-raises-ambitions-in-pbc-with-more-than-85-of-patients-on-treatment-achieving-alp-normalization-3396826 \u53c2\u8003\u6587\u732e 1. Kowdley. K,et al. Treatment with elafibranor to normalize alkaline phosphatase in patients with primary biliary cholangitis and incomplete response to ursodeoxycholic acid: Results<\/p>\n","protected":false},"author":69,"template":"","categories":[35],"tags":[],"class_list":["post-104278","press_release","type-press_release","status-publish","has-post-thumbnail","hentry","category-35","entry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u5168\u7403\u8d44\u8baf\uff1a\u4f9d\u975e\u5170\u8bfa\u53d1\u5e03\u6700\u65b0\u7a81\u7834\u6027\u7814\u7a76\u6570\u636e\uff0c\u63a8\u52a8\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\u6cbb\u7597\u8fc8\u5411\u66f4\u9ad8\u76ee\u6807\uff0c\u7814\u7a76\u4e2d\u8d85\u8fc785%\u7684\u6cbb\u7597\u60a3\u8005\u5b9e\u73b0\u78b1\u6027\u78f7\u9178\u9176\u6b63\u5e38\u5316 - China<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ipsen.com\/cn\/press-releases\/%e5%85%a8%e7%90%83%e8%b5%84%e8%ae%af%ef%bc%9a%e4%be%9d%e9%9d%9e%e5%85%b0%e8%af%ba%e5%8f%91%e5%b8%83%e6%9c%80%e6%96%b0%e7%aa%81%e7%a0%b4%e6%80%a7%e7%a0%94%e7%a9%b6%e6%95%b0%e6%8d%ae%ef%bc%8c%e6%8e%a8\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u5168\u7403\u8d44\u8baf\uff1a\u4f9d\u975e\u5170\u8bfa\u53d1\u5e03\u6700\u65b0\u7a81\u7834\u6027\u7814\u7a76\u6570\u636e\uff0c\u63a8\u52a8\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\u6cbb\u7597\u8fc8\u5411\u66f4\u9ad8\u76ee\u6807\uff0c\u7814\u7a76\u4e2d\u8d85\u8fc785%\u7684\u6cbb\u7597\u60a3\u8005\u5b9e\u73b0\u78b1\u6027\u78f7\u9178\u9176\u6b63\u5e38\u5316 - China\" \/>\n<meta property=\"og:description\" content=\"\u3000\u3000\u76ca\u666e\u751f\u8fd1\u65e5\u516c\u5e03\u4e86ELSPIRE \u2162\u671f\u7814\u7a76\u7684\u6700\u65b0\u7a81\u7834\u6027\u7814\u7a76\u6570\u636e\uff0c\u8be5\u7814\u7a76\u7eb3\u5165\u4e86\u78b1\u6027\u78f7\u9178\u9176\uff08ALP\uff09\u6c34\u5e73\u4e3a\u6b63\u5e38\u503c\u4e0a\u9650\uff08ULN\uff091\u81f31.67\u500d\u7684\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\uff08PBC\uff09\u60a3\u8005\u3002ALP\u662f\u8861\u91cf\u75be\u75c5\u6d3b\u52a8\u5ea6\u7684\u4e00\u9879\u751f\u5316\u6307\u6807\u3002\u7b2c52\u5468\u65f6\uff0c85.3%\u63a5\u53d7\u4f9d\u975e\u5170\u8bfa\u6cbb\u7597\u7684\u60a3\u8005ALP\u8fbe\u5230\u6b63\u5e38\u6c34\u5e73\uff0c\u5b89\u6170\u5242\u7ec4\u4e3a23.3%\uff08p&lt;0.0001\uff09\u3002\u7814\u7a76\u7ed3\u679c\u4f5c\u4e3a\u6700\u65b0\u7a81\u7834\u6027\u7814\u7a76\u6570\u636e\uff0c\u57282026\u5e74\u7f8e\u56fd\u809d\u75c5\u7814\u7a76\u5b66\u4f1a\uff08AASLD\uff09\u809d\u75c5\u5e74\u4f1a\uff08The Liver Meeting\u00ae 2026\uff09\u4e0a\u516c\u5e03\uff0c\u5e76\u540c\u6b65\u53d1\u8868\u4e8e\u300a\u809d\u810f\u75c5\u5b66\u300b\uff08HEPATOLOGY\uff091\u3002\u6b64\u5916\uff0c\u8fd9\u4e9b\u6db5\u76d6\u66f4\u5e7f\u6cdb\u60a3\u8005\u4eba\u7fa4\u7684\u6570\u636e\u6b63\u5728\u5411\u76d1\u7ba1\u673a\u6784\u9012\u4ea4\u3002 \u3000\u3000\u7f8e\u56fd\u77e5\u540d\u809d\u75c5\u7814\u7a76\u4e2d\u5fc3Liver Institute Northwest\u3001Velocity \u4e34\u5e8a\u7814\u7a76\u673a\u6784\u53ca\u534e\u76db\u987f\u5dde\u7acb\u5927\u5b66\u533b\u5b66\u535a\u58ebKris V. 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Kowdley. K,et al. 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