{"id":3670,"date":"2023-06-16T00:25:11","date_gmt":"2023-06-15T22:25:11","guid":{"rendered":"https:\/\/www.ipsen.com\/annualreport\/press-releases\/ipsen-delivers-strong-sales-growth-for-the-first-nine-months-and-improves-its-full-year-guidance\/"},"modified":"2023-06-16T00:25:11","modified_gmt":"2023-06-15T22:25:11","slug":"ipsen-delivers-strong-sales-growth-for-the-first-nine-months-and-improves-its-full-year-guidance","status":"publish","type":"press_release","link":"https:\/\/www.ipsen.com\/annualreport\/press-releases\/ipsen-delivers-strong-sales-growth-for-the-first-nine-months-and-improves-its-full-year-guidance\/","title":{"rendered":"Ipsen delivers strong sales growth for the first nine months and improves its full-year guidance"},"content":{"rendered":"<p><b>Paris (France), 21\u00a0October 2021\u00a0<\/b>\u2013 Ipsen (Euronext: IPN; ADR: IPSEY), a global specialty-driven biopharmaceutical group, publishes its sales performance for the third quarter of 2021 and the year to date.<\/p>\n<p><b>Sales summary<\/b><br \/>(unaudited IFRS consolidated sales)<\/p>\n<table style=\"border-collapse: collapse;width:731.042px;border-collapse:collapse\">\n<tr>\n<td rowspan=\"3\">\u00a0<\/td>\n<td>\u00a0<\/td>\n<td colspan=\"4\"><b>Third Quarter<\/b><\/td>\n<td>\u00a0<\/td>\n<td colspan=\"4\"><b>Year To Date<\/b><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<\/td>\n<td><b>2021<\/b><\/td>\n<td><b>2020<\/b><\/td>\n<td colspan=\"2\"><b>% change<\/b><\/td>\n<td>\u00a0<\/td>\n<td><b>2021<\/b><\/td>\n<td><b>2020<\/b><\/td>\n<td colspan=\"2\"><b>% change<\/b><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<\/td>\n<td><b>\u20acm<\/b><\/td>\n<td><b>\u20acm<\/b><\/td>\n<td><b>Actual<\/b><\/td>\n<td><b>CER<\/b><sup>1<\/sup><\/td>\n<td>\u00a0<\/td>\n<td><b>\u20acm<\/b><\/td>\n<td><b>\u20acm<\/b><\/td>\n<td><b>Actual<\/b><\/td>\n<td><b>CER<\/b><sup>1<\/sup><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<\/tr>\n<tr>\n<td>Specialty Care<\/td>\n<td>\u00a0<\/td>\n<td>667.8<\/td>\n<td>580.5<\/td>\n<td>15.0%<\/td>\n<td>15.1%<\/td>\n<td>\u00a0<\/td>\n<td>1,912.3<\/td>\n<td>1,747.6<\/td>\n<td>9.4%<\/td>\n<td>12.5%<\/td>\n<\/tr>\n<tr>\n<td>Consumer Healthcare<\/td>\n<td>\u00a0<\/td>\n<td>59.6<\/td>\n<td>52.8<\/td>\n<td>12.8%<\/td>\n<td>12.2%<\/td>\n<td>\u00a0<\/td>\n<td>165.5<\/td>\n<td>154.0<\/td>\n<td>7.5%<\/td>\n<td>9.8%<\/td>\n<\/tr>\n<tr>\n<td><b>Total Sales<\/b><\/td>\n<td>\u00a0<\/td>\n<td><b>727.4<\/b><\/td>\n<td><b>633.3<\/b><\/td>\n<td><b>14.9%<\/b><\/td>\n<td><b>14.9%<\/b><\/td>\n<td>\u00a0<\/td>\n<td><b>2,077.7<\/b><\/td>\n<td><b>1,901.6<\/b><\/td>\n<td><b>9.3%<\/b><\/td>\n<td><b>12.3%<\/b><\/td>\n<\/tr>\n<\/table>\n<p><b>Highlights<\/b><\/p>\n<ul>\n<li style=\"margin-bottom:3px\">Total sales growth of 12.3% at CER<sup>1<\/sup>\u00a0in the year to date, or 9.3% as reported, to \u20ac2,077.7m. In the third quarter, total sales of \u20ac727.4m represented growth of 14.9% at CER<sup>1<\/sup>\u00a0and as reported<\/li>\n<li style=\"margin-bottom:3px\">An increase in Specialty Care sales in the year to date of 12.5%<sup>1<\/sup>\u00a0to \u20ac1,912.3m, driven by the growth of Somatuline\u00ae\u00a0(<em>lanreotide<\/em>), Cabometyx\u00ae\u00a0(<em>cabozantinib<\/em>), Decapeptyl\u00ae\u00a0(<em>triptorelin<\/em>) and Dysport\u00ae\u00a0(<em>botulinum toxin type\u00a0A<\/em>)<\/li>\n<li style=\"margin-bottom:3px\">Consumer Healthcare sales growth of 9.8%<sup>1<\/sup>\u00a0in the year to date to \u20ac165.5m, reflecting the performance of Smecta\u00ae\u00a0(<em>diosmectite<\/em>) and the strong COVID-19 recovery<\/li>\n<li style=\"margin-bottom:3px\">Strong business-development activity, with agreements in Oncology and Neuroscience<\/li>\n<li style=\"margin-bottom:3px\">Full-year guidance upgraded:\n<ul>\n<li style=\"margin-bottom:3px\">Total sales growth<sup>1<\/sup>\u00a0\u00a0: greater than +11.0% (prior guidance: greater than +8.0%)<\/li>\n<li style=\"margin-bottom:3px\">Core operating margin<sup>2<\/sup>: around 34% (prior guidance: around 32.0%)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><b>David Loew, Chief Executive Officer, commented:<\/b><br \/>\u201cWe delivered a strong performance in the third quarter, reflecting the implementation of our new strategy and improving levels of commercial execution. Somatuline and Cabometyx growth was particularly encouraging, while strong sales of Dysport continue to underpin confidence in the potential of this important medicine. Despite regulatory delays for palovarotene in FOP, the replenishment of our pipeline gathered pace, with our external-innovation strategy providing an exciting platform for sustainable top-line growth.<br \/>We continue to maximize our brands, strengthen the pipeline and are driving efficiencies across our business. This strategy, built on our culture and an unrelenting focus on patients, is delivering strong results, giving us the confidence to upgrade this year\u2019s guidance while remaining focused on the long-term Ipsen growth story.\u201d<\/p>\n<p><b>FY 2021 guidance<\/b><br \/>Based on the strong performance in the year to date, the gradual easing of the COVID-19 pandemic and a limited impact from the launch of generic lanreotide in Europe, the Company today upgrades its financial guidance for FY\u00a02021:<\/p>\n<table style=\"border-collapse: collapse;width:731.042px;border-collapse:collapse\">\n<tr>\n<td>\u00a0<\/td>\n<td><b>New guidance<\/b><\/td>\n<td><b>Prior guidance<\/b><\/td>\n<\/tr>\n<tr>\n<td>Total sales growth<sup>3<\/sup><\/td>\n<td>Greater than 11.0%<\/td>\n<td>Greater than 8.0%<\/td>\n<\/tr>\n<tr>\n<td>Core operating margin<sup>4<\/sup><\/td>\n<td>Around 34%<\/td>\n<td>Around 32.0%<\/td>\n<\/tr>\n<\/table>\n<p><b>Currency impact<\/b><br \/>Ipsen anticipates an unchanged adverse impact of 2% from currencies on total sales in FY 2021, based on the level of exchange rates at the end of September 2021.<\/p>\n<p><b>Business development<\/b><br \/>Since the publication of the H1 2021 results announcement, Ipsen signed two agreements in line with its external-innovation focus on strengthening the pipeline:<\/p>\n<p><u>METTL3 (Oncology)<\/u><br \/>In October 2021, Ipsen and Accent Therapeutics (Accent) signed an exclusive worldwide-collaboration agreement to research, develop, manufacture, and commercialize Accent\u2019s pre-clinical stage METTL3 program. This collaboration reinforces Ipsen\u2019s expansion into hematological malignancies, with a focus on acute myeloid leukemia.<br \/><u>Spherical Nucleic Acids (Neuroscience)<\/u><br \/>In August 2021, Ipsen entered into an exclusive collaboration agreement with Exicure to research, develop, and commercialize novel Spherical Nucleic Acids as potential investigational treatments for Huntington\u2019s disease and Angelman syndrome.<\/p>\n<p><b>Palovarotene<\/b><br \/>In August 2021, Ipsen withdrew the New Drug Application (NDA) for palovarotene in FOP<sup>5<\/sup>, after discussions with the U.S. Food and Drug Administration (FDA). This followed ongoing dialogue with the FDA after the acceptance of the NDA for Priority Review, announced in May 2021. During the review and the ongoing dialogue, it was recognized that additional analyses and evaluation of data collected from Ipsen\u2019s Phase\u00a0III MOVE and FOP program would be required to progress and complete the review process. It was agreed that it would not be possible to complete this within the NDA review cycle. Upon successful completion of the additional data analyses, Ipsen currently anticipates regulatory resubmission in the U.S. in H1 2022. A \u2018clock-stop\u2019 was also granted by the European Medicines Agency.<\/p>\n<p><b>Conference call<\/b><br \/>A conference call and webcast for investors and analysts will begin at 2:30pm Paris time today. Participants should dial in to the call early and can register\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=O4Srdc4MAG99cyPMsW-N4Epn61CGoOUw7SRxs-8V_SxrDSBNppccyTRcYsJbcxV08FBgu3D5p3Q3dSTfMg_qt9pwTorWG3f7t20x-MKiKc4=\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\"><b>here<\/b><\/a>; a recording will be available on\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=H5BbOfvtsc-tlp-hZBW1HdLLQmpPHRhz7c66TR0-bVS7tl33RdfPVIf7yRAm6hnRCunWnMnqbsUgUY5-8yEiMsnkrNOMktQw6tN0mVIDHW8=\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\"><b>ipsen.com<\/b><\/a>, while the webcast can be accessed\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=O4Srdc4MAG99cyPMsW-N4FwPxfHzjVFrUPkhxBI3I2squUhBEvM9autxpL9SxwVmWuDtoUBQpztdYIju3U1LFb-5UAzUcGr11xWwkfgSdBw=\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\"><b>here<\/b><\/a>. The event ID is 4312698.<\/p>\n<p><b>Calendar<\/b><br \/>The Company intends to publish its FY 2021 results on 11\u00a0February 2022.<\/p>\n<p><b>Notes<\/b><br \/>All financial figures are in \u20ac\u00a0millions (\u20acm). The performance shown in this announcement covers the nine-month period to 30\u00a0September 2021 (the year to date or YTD 2021) and the three-month period to 30\u00a0September 2021 (the third quarter or Q3\u00a02021), compared to nine-month period to 30\u00a0September 2020 (YTD 2020) and the three-month period to 30\u00a0September 2020 (Q3\u00a02020) respectively, unless stated otherwise. Commentary is based on the performance in YTD 2021, unless stated otherwise.<\/p>\n<p><b>Ipsen<\/b><br \/>Ipsen is a global, mid-sized biopharmaceutical company focused on transformative medicines in Oncology, Rare Disease and Neuroscience; it also has a well-established Consumer Healthcare business. With total sales of over \u20ac2.5bn in FY 2020, Ipsen sells more than 20\u00a0medicines in over 115\u00a0countries, with a direct commercial presence in more than 30\u00a0countries. The Company\u2019s research and development efforts are focused on its innovative and differentiated technological platforms located in the heart of leading biotechnological and life-science hubs: Paris-Saclay, France; Oxford, U.K.; Cambridge, U.S.; Shanghai, China. Ipsen has c.5,700 colleagues worldwide and is listed in Paris (Euronext: IPN) and in the U.S. through a Sponsored Level\u00a0I American Depositary Receipt program (ADR: IPSEY). For more information, visit\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=H5BbOfvtsc-tlp-hZBW1HbaosOLz1h8b8DaQ-WL5X2ASE-KNPm-rilELApjjLxGQezQGhzq_i_qZvFi1NSFoBQ==\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\"><b>ipsen.com<\/b><\/a>.<\/p>\n<table style=\"border-collapse: collapse;width:731.042px;border-collapse:collapse\">\n<tr>\n<td><b>Contacts<\/b><\/td>\n<td>\u00a0<\/td>\n<\/tr>\n<tr>\n<td><b><u>Investors<\/u><\/b><\/td>\n<td>\u00a0<\/td>\n<\/tr>\n<tr>\n<td>   <b>Craig Marks<\/b><br \/>Vice President, Investor Relations<br \/>+44 7584 349 193               <\/td>\n<td>   <b>Adrien Dupin de Saint-Cyr<\/b><br \/>Investor Relations Manager<br \/>+33 6 64 26 17 49               <\/td>\n<\/tr>\n<tr>\n<td><b><u>Media<\/u><\/b><\/td>\n<td>\u00a0<\/td>\n<\/tr>\n<tr>\n<td>   <b>Gwenan White<\/b><br \/>Executive Vice President, Communications and Public Affairs<br \/>+44 7876 391 429               <\/td>\n<td>   <b>Fanny Allaire<\/b><br \/>Global Communications Director<br \/>+ 33 6 08 91 92 55               <\/td>\n<\/tr>\n<\/table>\n<p> \u00a0<\/p>\n<p><sup>1<\/sup>\u00a0\u00a0\u00a0\u00a0\u00a0 At constant exchange rates (CER), which exclude any foreign-exchange impact by recalculating the performance for the relevant period by applying the exchange rates used for the prior period.<br \/><sup>2<\/sup>\u00a0\u00a0\u00a0\u00a0\u00a0 As a ratio of core operating income to total sales.<br \/><sup>3<\/sup>\u00a0\u00a0\u00a0\u00a0\u00a0 At CER, which exclude any foreign-exchange impact by recalculating the performance for the relevant period by applying the\u00a0exchange rates used for the prior period.<br \/><sup>4<\/sup>\u00a0\u00a0\u00a0\u00a0\u00a0 As a ratio of core operating income to total sales.<br \/><sup>5<\/sup>\u00a0\u00a0\u00a0\u00a0\u00a0 Fibrodysplasia ossificans progressiva.<\/p>\n<p>\u00a0<\/p>\n<p id=\"gnw_attachments_section-header\">\n    <strong>Attachment<\/strong>\n<\/p>\n<ul id=\"gnw_attachments_section-items\">\n<li>\n        <a target=\"_blank\" href=\"https:\/\/www.globenewswire.com\/Tracker?data=s8lCAACJhe5cDmbLJmvaE1z8D-fk3wynA3e8P1ZuJ4xJEY6x0ApkpcRdRF937_M9w8xBYJKkVRdXNHHEss255zgTl2U37y4CipuN9i59smSgWeIPgpjMbX_3D-hxObBkzO31TVBiSH4UpVBOtepkyDV7p2qtv2g1sbxOwfgNKyG-yws0lbSNPaXd4HU12Ic2\" title=\"YTD-2021-sales-announcement\" rel=\"nofollow noopener\">YTD-2021-sales-announcement<\/a>\n      <\/li>\n<\/ul>\n<p><img src='https:\/\/ml-eu.globenewswire.com\/media\/MmQxN2M1MTktZmY2MS00MDUxLWIwYTktYTAwYmUwMDEyMWE2LTEwMTA5NDM=\/tiny\/Ipsen-SA.png' \/><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"template":"","categories":[],"tags":[],"class_list":["post-3670","press_release","type-press_release","status-publish","hentry","entry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - 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