{"id":6378,"date":"2025-07-31T09:23:22","date_gmt":"2025-07-31T07:23:22","guid":{"rendered":"https:\/\/www.ipsen.com\/annualreport\/a-conversation-with-david-loew\/"},"modified":"2026-05-18T08:46:29","modified_gmt":"2026-05-18T06:46:29","slug":"a-conversation-with-david-loew","status":"publish","type":"page","link":"https:\/\/www.ipsen.com\/annualreport\/a-conversation-with-david-loew\/","title":{"rendered":"A conversation with David Loew"},"content":{"rendered":"    <section class=\"sub-page-banner bg-color-enabled  banner-no-filter\" style=\"background: linear-gradient(93.64deg, #224A81 2.99%, #2797D3 97.01%)\">\n                <div class=\"container content-sec\">\n            <nav aria-label=\"breadcrumb banner-font-color-blue\">\n            <ol class=\"breadcrumb\">\n                <li class=\"breadcrumb-item\"><a href=\"https:\/\/www.ipsen.com\/annualreport\">Home<\/a><\/li><li class=\"breadcrumb-item active\"><a class=\"link-pointer-events-none\" href=\"#\" aria-current=\"page\">A conversation with David Loew<\/a><\/li><\/ol>\n            <\/nav>            <h1 class=\"hidden banner-font-color-white\">A conversation with David Loew<\/h1>\n            <p class=\"hidden banner-font-color-white\"><\/p>\n        <\/div>\n    <\/section>\n\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><!-- Text & Media Block Code -->\n<section class=\"two-col-section text-media-section\">\n    <div class=\"container two-section-innner \">\n        <div class=\"response-inner\" style=\"background-image: url('')\">\n            <div class=\"row \">\n                <div class=\"col-xs-12 col-sm-12 col-md-6\">\n                                                    <div class=\"img-video-section\">\n                                <img decoding=\"async\" \n                                    src=\"https:\/\/www.ipsen.com\/annualreport\/wp-content\/uploads\/sites\/3\/2026\/05\/01_DAVID-LOEW_IPSEN-COM_756x506pix.jpg\" \n                                    alt=\"\" \n                                >\n                            <\/div>\n                                        <\/div>\n                <div class=\" col-xs-12 col-sm-12 col-md-6\">\n                    <div class=\"section-content\">\n                        <div class=\"heading-dash\">\n                                                            <span class=\"dash\"><\/span>\n                                <h4 class=\"heading-para heading-four\" role=\"heading\" aria-level=\"2\">\n                                    Five years of turning ambition into impact                                <\/h4>\n                                                    <\/div>\n                                                <p>2025 marked five years of <em>Focus. Together. For patients and society. <\/em>Guided by this strategy, we have embarked on exciting new partnerships, expanded our pipeline and portfolio and shared promising data from our clinical trials. All of this broadened the range of options for patients living with difficult-to-treat conditions in oncology, rare disease and neuroscience.<\/p>\n<p><strong>David Loew, Ipsen\u2019s CEO, reflects on how we translate strategy into results. \u00a0<\/strong><\/p>\n                            <a \n                            aria-label=\" about Five years of turning ambition into impact\"  \n                                role=\"link\" \n                                class=\"btn-link hidden\"\n                                href=\"\" \n                                target=\"_self\"\n                            > \n                                 \n                            <\/a>\n\n                    <\/div>\n                <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/section>\n\n    <section class=\"title-text \">\n        <div class=\"container\">\n            <div class=\"title-text-inner\" style=\"background-color:#EDEBE4;\">\n\n                <!-- If heading is enabled then it's visible -->\n                <div class=\"text-head-dash visible\">\n                <h3 class=\"heading-three\" role=\"heading\" aria-level=\"2\">\n                        What have we achieved in the five years since the launch of our strategy?                    <\/h3>\n                <\/div>\n               \n                <!-- If description is enabled then it's visible -->\n                <div class=\"text-parbase visible\">\n                    <p>David Loew: We expanded our portfolio and delivered treatments where they are most needed. In 2020, we had approved medicines for 20 indications, and we\u2019re ending 2025 serving 32 indications.<\/p>\n<p>We\u2019ve achieved this by expanding our pipeline and drawing on our existing treatments and expertise. For example, this year our long-standing asset, Cabometyx\u00ae, was approved in a new indication in the E.U.: previously treated unresectable or metastatic neuroendocrine tumors.<\/p>\n<p>And we\u2019ve grown our core operating margin to 35.2% of total sales, giving us more resources for research and development and launching medicines. Last year, we issued our first public bond of \u20ac500 million, giving us even more firepower for external innovation.<\/p>\n<p>Now our pipeline is diversified and richer than ever. We\u2019re developing assets that have best- or first-in-class potential, leveraging our expertise at our global hubs. And we\u2019ve embarked on strategic partnerships, notably in 2021 with GENFIT, and in 2023 when we acquired Albireo, which laid the foundation for our work in rare liver disease. In December 2025, we partnered with IRICoR at the Universit\u00e9 de Montr\u00e9al and Simcere Zaiming, a leading oncology biotech.<\/p>\n<p>Ultimately, this is improving outcomes for patients. Take for example our rare liver disease franchise. In 2021, we set out with a goal: to develop treatment options for rare cholestatic conditions. We worked quickly, because there is no time to lose for these patients or their families. And only a few years later, we have two medicines approved in three rare cholestatic indications and the potential for additional indications. We\u2019ve built a leadership position in rare liver disease in record time.<\/p>\n<p>Along the way, we\u2019ve fostered a global culture of collaboration, excellence and impact. In 2025 we reached 30 Great Place to Work\u00ae certifications, and we achieved gender parity in our Executive Leadership Team. This was one of our core commitments we set ourselves in 2020, and I\u2019m proud that we\u2019ve fulfilled it.<\/p>\n                <\/div>\n\n                <!-- If button is enabled then it's visible -->\n                \n            <\/div>\n        <\/div>\n    <\/section>\n<\/div>\n<\/div>\n\n\n<!-- Text & Media Block Code -->\n<section class=\"two-col-section text-media-section\">\n    <div class=\"container two-section-innner section-reverse\">\n        <div class=\"response-inner\" style=\"background-image: url('')\">\n            <div class=\"row section-reverse\">\n                <div class=\"col-xs-12 col-sm-12 col-md-6\">\n                                                    <div class=\"img-video-section\">\n                                <img decoding=\"async\" \n                                    src=\"https:\/\/www.ipsen.com\/annualreport\/wp-content\/uploads\/sites\/3\/2026\/05\/Dublin-Ireland1.jpg\" \n                                    alt=\"\" \n                                >\n                            <\/div>\n                                        <\/div>\n                <div class=\" col-xs-12 col-sm-12 col-md-6\">\n                    <div class=\"section-content\">\n                        <div class=\"heading-dash\">\n                                                            <span class=\"dash\"><\/span>\n                                <h4 class=\"heading-para heading-four\" role=\"heading\" aria-level=\"2\">\n                                    What were some of Ipsen\u2019s stand-out achievements in 2025?                                <\/h4>\n                                                    <\/div>\n                                                <p>David Loew: It was a strong year, with \u20ac3.7 billion in total sales. All our therapeutic areas grew, especially Rare Disease where sales increased 102.5% compared to 2024. This was largely driven by quarter-on-quarter acceleration in sales of IQIRVO\u00ae, which just launched last year to treat primary biliary cholangitis, a rare liver disease.<\/p>\n<p>Our teams also shared clinical trial data around the world. Crucially, we had the IPN10200 proof-of-concept readout in aesthetics, which demonstrated that our proprietary recombinant molecule has a first-in-class, long-acting clinical profile. We are thrilled to begin Phase III trials of this potential breakthrough in aesthetics.<\/p>\n<p>We achieved regulatory milestones, like our submission of Ojemda\u00ae (tovorafenib) in pediatric low-grade glioma, which was accepted by the European Medicines Agency. In April 2026, it was approved in the E.U. as the first targeted therapy in relapsed or refractory pediatric low-grade glioma regardless of BRAF alteration.<\/p>\n<p>And we continued to find new external innovation opportunities. We acquired ImCheck Therapeutics, strengthening our leadership in oncology and building our expertise in hemato-oncology.<\/p>\n                            <a \n                            aria-label=\" about What were some of Ipsen\u2019s stand-out achievements in 2025?\"  \n                                role=\"link\" \n                                class=\"btn-link hidden\"\n                                href=\"\" \n                                target=\"_self\"\n                            > \n                                 \n                            <\/a>\n\n                    <\/div>\n                <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/section>\n\n    <section class=\"title-text \">\n        <div class=\"container\">\n            <div class=\"title-text-inner\" style=\"background-color:#EDEBE4;\">\n\n                <!-- If heading is enabled then it's visible -->\n                <div class=\"text-head-dash visible\">\n                <h3 class=\"heading-three\" role=\"heading\" aria-level=\"2\">\n                        What are you most looking forward to in 2026?                    <\/h3>\n                <\/div>\n               \n                <!-- If description is enabled then it's visible -->\n                <div class=\"text-parbase visible\">\n                    <p>David Loew: We\u2019re at the start of an exciting new phase, as we\u2019re anticipating three key data readouts and the addition of three new late-stage clinical programs to our pipeline.<\/p>\n<p>We\u2019ll be sharing data on corabotase in glabellar lines at the SCALE conference, and we will also get the phase II data in frontal head and lateral canthal lines in aesthetics. And we look forward to testing it further as a potential treatment for adult upper limb spasticity and chronic and episodic migraines.<\/p>\n<p>In the early and pre-clinical pipeline, we\u2019re investigating exciting new modalities that could transform standards of care. This includes MAP kinase inhibitors that block the growth and replication of cancer cells, antibody drug conjugates that deliver targeted treatment payloads and T cell activators that harness the body\u2019s own immune system to fight cancer.<\/p>\n<p>Beyond the pipeline, I\u2019m also pleased by our achievements in sustainability. We received certification from the Science Based Targets initiative, confirming our sustainability goals meet the highest standards and are grounded in science across our business. And as of last year, 100% of our electricity comes from renewable sources.<\/p>\n<p>And we will build on this energy with our new sustainability strategy. It focuses our efforts around four pillars: access to healthcare, human impact, climate action and responsible business. By concentrating our work in each of these areas, we aim to enhance our positive impact in the long term.<\/p>\n                <\/div>\n\n                <!-- If button is enabled then it's visible -->\n                \n            <\/div>\n        <\/div>\n    <\/section>\n\n\n<!-- Text & Media Block Code -->\n<section class=\"two-col-section text-media-section\">\n    <div class=\"container two-section-innner \">\n        <div class=\"response-inner\" style=\"background-image: url('')\">\n            <div class=\"row \">\n                <div class=\"col-xs-12 col-sm-12 col-md-6\">\n                                                    <div class=\"img-video-section\">\n                                <img decoding=\"async\" \n                                    src=\"https:\/\/www.ipsen.com\/annualreport\/wp-content\/uploads\/sites\/3\/2026\/05\/Balard1.jpg\" \n                                    alt=\"\" \n                                >\n                            <\/div>\n                                        <\/div>\n                <div class=\" col-xs-12 col-sm-12 col-md-6\">\n                    <div class=\"section-content\">\n                        <div class=\"heading-dash\">\n                                                            <span class=\"dash\"><\/span>\n                                <h4 class=\"heading-para heading-four\" role=\"heading\" aria-level=\"2\">\n                                    What comes next for Ipsen in 2027 and beyond?                                 <\/h4>\n                                                    <\/div>\n                                                <p>David Loew: Our strategy is having a huge impact, but that doesn\u2019t mean we can rest on our laurels. Our sustainable growth tomorrow depends on where we focus our efforts today. Looking ahead, we\u2019ll continue to seek out molecules with first- or best-in-class potential, work to develop them into treatments, and partner with healthcare systems to bring them to patients worldwide. That\u2019s our commitment, and as we\u2019ve shown this year, we\u2019re fully prepared to deliver on it.<\/p>\n                            <a \n                            aria-label=\" about What comes next for Ipsen in 2027 and beyond? \"  \n                                role=\"link\" \n                                class=\"btn-link hidden\"\n                                href=\"\" \n                                target=\"_self\"\n                            > \n                                 \n                            <\/a>\n\n                    <\/div>\n                <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/section>\n\n\t<!-- Ipsen Quotes Start -->\n\t<section class=\"quotes-section\" aria-label=\"quotes-section\">\n\t\t<div class=\"container\">\n\t\t\t\t\t\t<div class=\"quote-sec-inner\"    >\n\t\t\t\t\t<div class=\"row\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"column-1 col-xl-4 col-md-6 col-xs-12 \">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"quote-img\">\n\t\t\t\t\t\t\t\t\t\t\t<img \n\t\t\t\t\t\t\t\t\t\t\t\tsrc=\"https:\/\/www.ipsen.com\/annualreport\/wp-content\/uploads\/sites\/3\/2026\/05\/David-Leow-2026.png\" \n\t\t\t\t\t\t\t\t\t\t\t\talt=\" Profile \"\n\t\t\t\t\t\t\t\t\t\t\t>\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"column-2 col-xl-8 col-md-6 col-xs-12 \">\n\t\t\t\t\t\t\t\t<div class=\"quote-content\">\n\t\t\t\t\t\t\t\t\t<div class=\"quote-para \">\n\t\t\t\t\t\t\t\t\t\t<p class=\"para\">\n\t\t\t\t\t\t\t\t\t\t\t<p>\u201cOur sustainable growth tomorrow depends on where we focus our efforts today.\u201d<\/p>\n\t\t\t\t\t\t\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"quote-sign-div\">\n\t\t\t\t\t\t\t\t\t\t<div class=\"quote-author-div\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"quote-dash-div\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"quote-dash\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.ipsen.com\/leadership\/david-loew\/\" target=\"_blank\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"quote-author primary-blue\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tDavid Loew\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"quote-author-role\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tIpsen\u2019s CEO, reflects on the last year.\t\t\t\t\t\t\t\t\t\t\t\t<\/p> \n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n<!-- Ipsen Quotes End -->\n\n\n<!--Graphics Cards Carousel Start Here-->\n\n    <section class=\"graphic-card graphics-old-layout bg-color-disabled bg-image-disabled bg-video-disabled bg-mobile-video-img-disabled\"    data-displaycards=\"3\">\n                <div class=\"container\">\n            <div class=\"text-graph-inner\">\n                <div class=\"row\">\n                    <!--Graphic info section-->\n                    <div class=\"column-1 col-xl-12 col-md-12 col-sm-12\">\n                        <div class=\"text-graph-heading\">\n                        <h3 class=\"charcoal-grey visible heading-three\" role=\"heading\" aria-level=\"2\">\n                                Ipsen\u2019s 2026 outlook                            <\/h3>\n                            <p class=\"text-graph-para charcoal-grey hidden\"><\/p>\n                        <\/div>\n                    <\/div><!--Graphic info section over here -->\n\n                    <!--Graphic detail section-->\n                    <div class=\"column-2 col-xl-12 col-md-12 col-sm-12\">\n                        <!-- graphic-card carousel start here -->\n          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                                                                                                                                                                          <div class=\"text-graph-title\">\n                                                                                                                            <h4 role=\"heading\" aria-level=\"3\">&gt;13.0% <\/h4>\n                                                                                                                            <\/div>\n                                                                                                                                                                                                                                        <div class=\"text-graph-desc\">\n                                                                                                                        <p><p>total sales growth at CER<\/p>\n<\/p>\n                                                                                                                    <\/div>\n                                                                                                                <\/div>\n                                                                                                            <\/div>\n                                                                                                            <!-- Graphic Card With OLD layout end here -->\n                                                                                                                                                <\/div>\n\n                                                                                    <\/div>\n                                                                                                                                                            <div class=\"text-graphic\">\n                                                                                    <div 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                                                                                                                    <div class=\"text-graph-title\">\n                                                                                                                            <h4 role=\"heading\" aria-level=\"3\">&gt;35%<\/h4>\n                                                                                                                            <\/div>\n                                                                                                                                                                                                                                        <div class=\"text-graph-desc\">\n                                                                                                                        <p><p>core operating margin<\/p>\n<\/p>\n                                                                                                                   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                                            <div class=\"text-graph-title\">\n                                                                                                                            <h4 role=\"heading\" aria-level=\"3\">3 data readouts<\/h4>\n                                                                                                                            <\/div>\n                                                                                                                                                                                                                                        <div class=\"text-graph-desc\">\n                                                                                                                        <p><\/p>\n                                                                                                                    <\/div>\n                                                                                     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                                                                                                         <h4 role=\"heading\" aria-level=\"3\">3 new clinical programs in 2026<\/h4>\n                                                                                                                            <\/div>\n                                                                                                                                                                                                                                        <div class=\"text-graph-desc\">\n                                                                                                                        <p><\/p>\n                                                                                                                    <\/div>\n                                                                                                                <\/div>\n                                             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<\/div>\n        <\/div> <!--Container class ended here -->\n    <\/section>\n<!--Graphics Cards Carousel End Here-->\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":9,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-6378","page","type-page","status-publish","hentry","entry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>A conversation with David Loew<\/title>\n<meta name=\"description\" content=\"2025 marked five years of Focus. Together. For patients and society. Guided by this strategy, we have embarked on exciting new partnerships, expanded our pipeline and portfolio and shared promising data from our clinical trials. All of this broadened the range of options for patients living with difficult-to-treat conditions in oncology, rare disease and neuroscience.David Loew, Ipsen\u2019s CEO, reflects on how we translate strategy into results.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ipsen.com\/annualreport\/a-conversation-with-david-loew\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A conversation with David Loew\" \/>\n<meta property=\"og:description\" content=\"2025 marked five years of Focus. Together. For patients and society. Guided by this strategy, we have embarked on exciting new partnerships, expanded our pipeline and portfolio and shared promising data from our clinical trials. 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